Growing colonies of Penicillium Variabile have broad white edges consist of white mycelium. Young colonies appear blue-green or grey-green and white to cream or faintly pink on the reverse. As the colonies mature, the colour of the mycelium becomes gray. Colonies can spread broadly, reaching 20-30 mm in a week at 25 °C with light or moderate sporulation.
Penicillium Variabile is one of the 36 species of molds genetically identified in an index called ERMI that is an acronym for Environmental Relative Moldiness Index that uses qualitative and quantitative PCR (QPCR) analyses for fungi. PCR is basically the identification of mold species by DNA sequencing. More information on ERMI testing.
Typical Areas Found
Penicillium spinulosum is psychrophilic, meaning that it is able to grow and reproduce at low temperature, and xerophile as it can germinate in decreased water activity environment (down to 0.8 Aw) by producing compatible solutes using enzyme systems.
P. spinulosum is found worldwide and is most commonly isolated from soil. It has also been isolated from dextrin paste, distilled water containers, cotton yarn, walnut kernels, chrome tanned leather, vinyl wall covering, paracetamol tablet, diesel fuel and emulsion paint treated with chromate. P. spinulosum is highly resistant to heavy metals, tannins and acids, and can be isolated from substrata contaminated by those materials.
P. spinulosum is able to survive in acidic environment although growth will be impeded.
Mycotoxins Produced by Penicillium Spinulosum
No mycotoxin production by P. spinulosum has been reported or observed.
In vitro, P. spinulosum does not grow at 37 °C is believed to be unlikely to cause human infection due to its inability to grow at or beyond this temperature.
Peer Reviewed Study for Penicillium Spinulosum
The inflammatory potential of Penicillium spinulosum spores isolated from indoor air of a moisture-damaged building in mouse lungs was studied. To assess the potential of Penicillium spinulosum to evoke harmful respiratory effects, mice were exposed via a single dose via intratracheal instillation. Inflammation and toxicity in the lungs were evaluated over multiple periods.
See actual PubMed study